Just upload files you want to join together, reorder them with draganddrop if you need and click join files. Levofloxacin tablets 8199710 250 mg, 500 mg and 750 mg. Levaquin levofloxacin tablets levaquin levofloxacin oral. Levofloxacin, hemihydrate, usp, levofloxacin, levofloxacin qacid, levofloxacin, hemihydrate, usp, levofloxacin, levofloxacin q. Details of the supplier of the safety data sheet 2. Levofloxacin is a chiral fluorinated carboxyquinolone. Highlights of prescribing information these highlights do not include all the information needed to use levaquin safely and effectively.
Antibiotic against bacterial respiratory tract infections. Files must conform to the predeterminedschema in order to be. Material safety data sheet levofloxacin hemihydrate sc211735 hazard alert code key. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only. Levofloxacin undergoes limited metabolism in humans and is primarily excreted as unchanged drug in the urine. Section 1 identification of the substancemixture and of. Sds of levofloxacin, safety data sheets, cas 100986854. Uses of levofloxacin levofloxacin is a broad spectrum antibiotic of the fluoroquinolone drug class. Levofloxacin, sold under the trade names levaquin among others, is an antibiotic. Dissolve usp levofloxacin rs in ndesmethyl levofloxacin. Levaquin is used to treat different types of bacterial infections. Pdf joiner allows you to merge multiple pdf documents and images into a single pdf file, free of charge. Avelox moxifloxacin hydrochloride injection, for intravenous use. Antibacteriallevofloxacin reduced bacterial load compared with placebo by 4.
Aug 06, 2012 levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis. Please note, this oelade monograph also applies to levofloxacin hydrate cas rn 8199710. Levofloxacin is a broadspectrum antibiotic used in pharmacokinetic, antibiotic resistance, and resistance prevention studies. Sds of sulfadimethoxine sodium salt, safety data sheets, cas. February 26, 2010 copper metal page 3 of 5 eu safety phrases. Levofloxacin binding to serum proteins is independent of the drug concentration. Levofloxacin 250 mg filmcoated tablets levofloxacin 500 mg filmcoated tablets levofloxacin read all of this leaflet carefully before you start taking this medicine because it contains important. Levaquin levofloxacin tablets levaquin levofloxacin oral solution levaquin levofloxacin injection levaquin levofloxacin in 5% dextrose injection to reduce the development of drugresistant bacteria and maintain the effectiveness of levaquin levofloxacin and other antibacterial drugs, levaquin.
Safety and efficacy of levofloxacin versus ciprofloxacin for. Levaquin oral solution, 25 mgml is a multiuse selfpreserving aqueous solution of levofloxacin with ph ranging from 5. Levofloxacin api manufacturers suppliers drug master. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. Fluoroquinolones, including levaquin, are associated with an.
Medication guide levaquin what is the most important. Understanding and correcting msds file upload errors. Use of levofloxacin levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial dna gyrase, halting dna replication. Highlights of prescribing information these highlights do not include all the information needed to use levaquin. Chemicalbook provide chemical industry users with levofloxacin carboxylic acid boiling point melting point,levofloxacin carboxylic acid density msds formula use,if you also need to levofloxacin. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. Vonkaenel august 9, 2007 martindales merck index revision summary not applicable disclaimer. Material safety datasheet 9sections section 1 product information product identifier drytype transformer whmis classification optional product use electrical manufacturers name. Ciprofloxacin hydrochloride safety data sheet supersedes revision.
The solubility of levofloxacin in six solvents including ethanol, 1propanol, 2propanol, 1butanol, acetic acid and ethyl acetate in the temperature range of 288. Material levofloxacin tablets 250 mg, 500 mg and 750 mg manufacturer lupin limited goa 403 722 india distributor lupin pharmaceuticals, inc. Moxifloxacin is an antibiotic used in treatment of bacterial infections. Levofloxacin solution for infusion is only intended for slow intravenous infusion. This is the only antibiotics my body can take i have read all the bad things about this but let me tell you its a wonder drug for me i feel better within 24 hrs every time i take it the only side effect i get is the diarrhea but it comes afterwards. Medication student name anna greenberg medication ciprofloxacin cipro levofloxacin levaquin category class bacterial dna replication inhibitor, fluoroquinolone.
Find msds sheets to access any material safety data sheet search our free msds online database. I highly recommend this to anyone who cant handle many antibiotics. This belongs to a group of medicines called antibiotics. Measurement and correlation for solubility of levofloxacin in. By comparison, dermal levofloxacin concentrations in human subjects receiving 750 mg of levofloxacin averaged approximately 11. Levaquin and other antibacterial drugs, levaquin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. Levofloxacin is active against grampositive and gramnegative bacteria. Nitrogen msds material safety data sheet for nitrogen n2 reference. Prevent the products used to fight the fire from going into drains, sewers, or waterways. We investigated the safety and efficacy of levofloxacin compared with ciprofloxacin for the treatment of chronic bacterial prostatitis in chinese patients. Levofloxacin should be kept in a tightly closed container, protected from light. Format this msds was prepared in accordance with directive 200158ec. Use water to cool tanks, cisterns, or containers close to the heat source or fire.
Pelvic inflammatory disease unlabeled use cdc, 2010. Levofloxacin is contraindicated in children and growing adolescents see section 4. Exposure controls personal protection protective clothing. It inhibits dna gyrase type ii topoisomerase and topoisomerase iv, thereby. Pdf evaluation of levofloxacin safety in broiler chickens. The cdc recommends use as an alternative therapy only if standard parenteral cephalosporin therapy is not feasible. Show this safety data sheet to the doctor in attendance.
Levofloxacin fda prescribing information, side effects. Fluoroquinolones, including levaquin, are associated with. Systemic fluoroquinolones conversion to levofloxacin the medical staff pharmacy and therapeutics committee, with the support of the antimicrobial subcommittee, has approved the removal of intravenous iv and oral po ciprofloxacin and moxifloxacin from the inpatient formulary and the addition of ivpo levofloxacin. Levofloxacin is a fluoroquinolone antibiotic indicated for susceptible infections of various parts of the body including airways, eyes, eyelids, prostate, sinus, lungs, urinary tract, skin, and kidneys. Investigation of ofloxacin, an older drug that is the racemic mixture, found that the l form the s enantiomer is more active. The appearance of levaquin oral solution may range from clear yellow to clear greenishyellow. First aid measures material safety data sheet material levofloxacin. Remove contact lenses, if present and if it is easy to do. The new sds required by osha are being added daily.
Levaquin levofloxacin tablets levaquin levofloxacin. Levofloxacin oel fastrac with ade affygility solutions. Levofloxacin is stereochemically stable in plasma and urine and does not invert metabolically to its enantiomer, dofloxacin. Levofloxacin 5 mgml solution for infusion summary of. Msds document numbern000 revision dated 03 sept 96 in an emergency, call chemtrec at 8004249300 us. The effectiveness of levofloxacin is based on plasma concentrations achieved in humans, a surrogate endpoint reasonably likely to predict clinical benefit. See actual entry in rtecs for complete information.
Fluoroquinolones, including levaquin, are associated with an increased risk of tendinitis and tendon rupture in all ages. Identification of the substancemixture and of the companyundertaking product name. The present study was designed to investigate safety of levofloxacin 10 mgkg after repeated oral administration at 12 h interval for 14 days in broiler chicken 810 weeks old and weighing. This sheet is provided as technical information only. Safety data sheet 109200 moxifloxacin hydrochloride. Therapy with levaquin may be initiated before results of these tests are known. Levofloxacin diffuses through the bacterial cell wall and. Wash eyes with plenty of clean and cool water for at least 10 minutes while pulling eyelids up, and seek medical assistance. Material safety data sheet prepared according to 29 cfr 1910.
We continually provide comprehensive safety and regulatory data on our safety data sheets promoting safe usage and handling of our products. Levaquin levofloxacin is a fluoroquinolone florokwinolone antibiotic that fights bacteria in the body. Levaquin, call your healthcare provider right away. Levofloxacin is a third generation fluoroquinolone antibacterial agent with a broad spectrum activity against. If inhaled if breathed in, move person into fresh air. Levofloxacin is indicated for inhalational anthrax postexposure to reduce the incidence or progression of disease following exposure to aerosolized bacillus anthracis. The information and recommendations set forth are made in good faith and believed to be accurate as of the date of preparation. It is used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, h.
Levofloxacin tablets contain a medicine called levofloxacin. See what is the most important information i should know about levaquin. The data on this material safety data sheet relate only to the specific material herein and do not relate to use in combination with any other material or process. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial dna gyrase, halting dna replication.
Levaquin levofloxacin tablet, film coated janssen pharmaceuticals, inc. Levofloxacin is a broadspectrum, thirdgeneration fluoroquinolone antibiotic and optically active lisomer of ofloxacin with antibacterial activity. Ciprofloxacin hydrochloride investigated as a drug. Mixture relevant identified uses of the substance or mixture and uses advised against intended use. First aid measures material safety data sheet material levofloxacin tablets 250 mg, 500 mg and 750 mg manufacturer lupin limited goa 403 722 india.
Levofloxacin hemihydrate sc211735 hazard alert code key. Levofloxacin hemihydrate, levaquin hydrate, tavanic hydrate, quixin hydrate, iquix hydrate. Capitals indicate lifethreatening, underlines indicate most frequent. As with other drugs in this class, some strains of. Systemic fluoroquinolones conversion to levofloxacin. It is indicated that the solubility data of levofloxacin in selected solvents increase with increasing temperature. Only select registry of toxic effects of chemical substances rtecs data is presented here.
In case of skin contact wash off with soap and plenty of water. Pharmaceutical product used as antibiotic agent details of the supplier of the safety data sheet 2. Sigmaaldrich offers a number of levofloxacin products. The information, data, recommendations, and suggestions appearing in this material safety data sheet msds andor in. You should use sunscreen and wear a hat and clothes that cover your skin if you have to be in sunlight. Extreme high moderate low section 1 chemical product and company identification product name levofloxacin hemihydrate statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting dna gyrase bacterial topoisomerase ii, an enzyme required for dna replication, rna transcription, and repair of. Levaquin oral solution contains the following inactive ingredients. Extreme high moderate low section 1 chemical product and company identification product name levofloxacin.
This product does not contain any chemicals known to the state of california to cause cancer, birth defects, or any other reproductive harm. The pharmacokinetics of levofloxacin lvfx, dr3355, the optically active component lisomer of ofloxacin, after a single oral administration of 100mg were studied in a total of 23 patients. Levaquin may cause serious side effects, including. Health levofloxacin is contraindicated in persons with known hypersensitivity to levofloxacin, or other quinolone antibacterials. Buy levofloxacin hemihydrate cas 8199710, an antibiotic against gramnegative organisms, from santa cruz. Levofloxacin c18h20fn3o4 cid 149096 structure, chemical names. Page 3 of 10 last updated march 31, 2016 cepi helpful hints understanding and correcting msds file upload errors interpreting errors. We have two ways to help you find safety data sheets. Page 3 of 5 7 handling and storage precautions for safe handling. The infusion time must be at least 30 minutes for 250 mg or 60 minutes for 500 mg levofloxacin see section 4. National library of medicines medical subject headings online file mesh, 2012.1073 422 195 387 228 1477 71 1322 314 1032 801 1175 791 1041 850 443 87 666 610 583 126 399 1431 1097 282 649 121 1328 1182 1169 630 22